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Mental Health Service Use Among Adolescents Following Participation in a Randomized Clinical Trial for Depression

机译:参加抑郁症随机临床试验后青少年的心理健康服务使用

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摘要

Major depressive disorder (MDD) is a common disorder among adolescents. The Treatment for Adolescents with Depression Study (TADS) was a randomized controlled trial to examine the efficacy of fluoxetine and cognitive-behavioral therapy (CBT), separately and together, compared with placebo, in adolescents 12 to 17 years of age. The Survey of Outcomes Following Treatment for Adolescent Depression (SOFTAD) was designed as a naturalistic follow-up of participants in TADS. The aims of the current analyses are to describe mental health service use during the SOFTAD period. There were 196 adolescents recruited from 12 TADS sites. The Schedule for Affective Disorders and Schizophrenia for School-Age-Children-Present and Lifetime Version was used for clinical diagnoses. Participants completed a psychiatric treatment log and the Child and Adolescent Services Assessment to assess service use. 58% received psychotherapy or nonstimulant psychotropic medication during SOFTAD. Youth with recurrent MDD had higher rates of treatment compared to youth without recurrent MDD (71% vs. 45%). However, nearly one third of the adolescents in the study did not receive treatment for a recurrent episode of depression. Service use differed by gender for those with recurrent MDD, with female participants (79%) receiving treatment at higher rates than male participants (55%), although there was no significant difference in depression severity between genders. Younger participants with recurrent MDD had higher odds of receiving psychotherapy. Use of psychotherapy and psychotropics following recurrence of depression appears to be influenced by age and gender. Even when youth respond well to treatment, a sizeable percentage are likely to experience a subsequent episode that may go untreated.
机译:重度抑郁症(MDD)是青少年中的常见疾病。青少年抑郁症治疗研究(TADS)是一项随机对照试验,旨在检查氟西汀和认知行为疗法(CBT)与安慰剂相比在12至17岁青少年中的疗效,分别与安慰剂比较。青少年抑郁症治疗后的结果调查(SOFTAD)被设计为TADS参与者的自然随访。当前分析的目的是描述SOFTAD期间心理健康服务的使用。从12个TADS站点招募了196名青少年。现行的学龄儿童和终身版本的情感障碍和精神分裂症的时间表用于临床诊断。参加者填写了精神病治疗记录和“儿童和青少年服务评估”以评估服务使用情况。 58%的患者在SOFTAD期间接受了心理疗法或非兴奋性精神药物治疗。与没有复发性MDD的青年相比,患有复发性MDD的青年的治疗率更高(分别为71%和45%)。但是,研究中将近三分之一的青少年未接受针对抑郁症复发的治疗。复发性MDD患者的服务使用因性别而异,女性参与者(79%)接受治疗的比例高于男性参与者(55%),尽管性别之间的抑郁严重程度没有显着差异。患有复发性MDD的年轻参与者接受心理治疗的几率更高。抑郁症复发后使用心理疗法和精神药物似乎受年龄和性别的影响。即使青年人对治疗反应良好,也有相当大的百分比可能会经历随后的发作而可能不予治疗。

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