Efficacy of Sustained Combination Therapy for at Least 6 Months with Thiopurines and Infliximab in Patients with Ulcerative Colitis in Clinical Remission: A Retrospective Multicenter French Experience

摘要

Background and Aims: Long-term benefits of combination therapy (combotherapy) with infliximab (IFX) and azathioprine (AZA) have been less studied in ulcerative colitis (UC) than in Crohn's disease. The aim of the present study was to determine UC disease activity in patients who received at least 6 months of combotherapy, and whether cotreatment for more than 6 months was useful in these patients.