Ultralow-Dose Abdominal Computed Tomography: Comparison of 2 Iterative Reconstruction Techniques in a Prospective Clinical Study

摘要

Computed tomography (CT) radiation dose is considered one of the most important safety concerns with modern medicine. A goal of ultralow-dose (ULD) radiation dose has been advocated by several federal agencies and national institutes because this would be below the average annual dose from background radiation. The Biologic Effects of Ionizing Radiation report no. 7 and linear-no-threshold model supported that "population" risk of cancer incidence decreases as the radiation dose to the patient decreases. Recent National Institute of Biomedical Imaging and Bioengineering meeting has also advocated the goal of achieving ULD radiation dose. In addition, several studies have already shown dose reduction to less than 1 mSv, especially cardiac and limited high-contrast clinical indications, such as Crohn disease, lung nodules evaluation, and scoliosis. Consequently, several efforts have been made to decrease the necessary radiation dose with CT scanning. Iterative reconstruction techniques (IRTs) have enabled dose reduction by reducing image noise while preserving image quality compared to conventional filtered back projection (FBP) based image reconstruc-tion. Potentially, to this end, several different types of IRT have recently become available.