EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer

Dunne Philip D.; Dasgupta Sonali; Blayney Jaine K.; McArt Darragh G.; Redmond Keara L.; Weir Jessica-Anne; Bradley Conor A.; Sasazuki Takehiko; Shirasawa Senji; Wang Tingting; Srivastava Supriya; Ong Chee Wee; Arthur Ken; Salto-Tellez Manuel; Wilson Richard H.; Johnston Patrick G.; Van Schaeybroeck Sandra

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EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer

机译：EphA2表达是结直肠癌的迁移和侵袭的关键驱动因素和不良的预后标志。

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Purpose: EphA2, a member of the Eph receptor tyrosine kinases family, is an important regulator of tumor initiation, neovascularization, and metastasis in a wide range of epithelial and mesenchymal cancers; however, its role in colorectal cancer recurrence and progression is unclear.

机译：目的：EphA2是Eph受体酪氨酸激酶家族的成员，是多种上皮和间充质癌中肿瘤起始，新血管形成和转移的重要调节剂;然而，其在结直肠癌复发和进展中的作用尚不清楚。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2016年第1期|共13页
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Dunne Philip D.; Dasgupta Sonali; Blayney Jaine K.; McArt Darragh G.; Redmond Keara L.; Weir Jessica-Anne; Bradley Conor A.; Sasazuki Takehiko; Shirasawa Senji; Wang Tingting; Srivastava Supriya; Ong Chee Wee; Arthur Ken; Salto-Tellez Manuel; Wilson Richard H.; Johnston Patrick G.; Van Schaeybroeck Sandra;
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正文语种 eng
中图分类肿瘤学;
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1. EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer [J] . Dunne Philip D., Dasgupta Sonali, Blayney Jaine K., Clinical cancer research: an official journal of the American Association for Cancer Research . 2016,第1期

机译：EphA2表达是结直肠癌的迁移和侵袭的关键驱动因素和不良的预后标志。
2. Overexpression of LAMC2 predicts poor prognosis in colorectal cancer patients and promotes cancer cell proliferation, migration, and invasion [J] . Dandan Huang, Changzheng Du, Dengbo Ji, Tumour biology : . 2017,第6期

机译：LAMC2的过表达预测结直肠癌患者的预后不良，并促进癌细胞的增殖，迁移和侵袭
3. Vascular Invasion and Stromal S100A4 Expression at the Invasive Front of Colorectal Cancer are Novel Determinants and Tumor Prognostic Markers [J] . Tamotsu Sugai, Noriyuki Yamada, Makoto Eizuka, Journal of Cancer . 2017,第9期

机译：血管入侵和结直肠癌侵袭前的血管侵袭和基质S100A4表达是新的决定因素和肿瘤预后标志物
4. A Panel of Prognostic Molecular Markers in Colorectal Cancer [C] . K. Ivanov, N. Kolev, A. Tonev, International Society of University Colon and Rectal Surgeons . 2008

机译：结直肠癌预后分子标记组
5. Development of novel biomarkers in cancer: Detection of circulating miR-141 as a potential prognostic marker for prostate cancer. [D] . Gonzales, Jason Cadaoas. 2010

机译：癌症中新型生物标志物的开发：检测循环miR-141作为前列腺癌的潜在预后标志物。
6. EphA2 expression is a key driver of migration and invasion and a poor prognostic marker in colorectal cancer [O] . Philip D. Dunne, Sonali Dasgupta, Jaine K. Blayney, -1

机译：EphA2表达是结直肠癌迁移和侵袭的关键驱动因素也是不良的预后指标
7. EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer [O] . Dunne, Philip D, Dasgupta, Sonali, Blayney, Jaine K, 2016

机译：EphA2表达是结直肠癌的迁移和侵袭的关键驱动因素和不良的预后标志。

EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer

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