Troponin I and cardiovascular risk stratification in patients with testicular cancer. Clinical Oncology dosage/*adverse effects

摘要

To the Editor: We have read the work of Nuver et al1 with great interest. The authors point out that long-term survivors of testicular cancer have an increased risk for cardiovascular events, and conclude that increase in von Willebrand factor plasma levels, and in the intima-media thickness of carotid artery, may predict cardiovascular complications in this population. Moreover, cardiac troponin I (Tnl) was measured in 37 patients at least once during each chemotherapy course. Ten patients (27%) showed an increase of this marker and three of those patients (30%) experienced a cardiovascular event during the study period (two acute myocardial infarctions and one acute pulmonary embolism). However, the authors have not grasped the relevant clinical implications of these findings.