Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer

Rosendahl Ann H.; Perks Claire M.; Zeng Li; Markkula Andrea; Simonsson Maria; Rose Carsten; Ingvar Christian; Holly Jeff M. P.; Jernstrom Helena

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Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer

机译：咖啡因和咖啡酸抑制乳腺癌的生长并改变雌激素受体和胰岛素样生长因子I受体的水平

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Purpose: Epidemiologic studies indicate that dietary factors, such as coffee, may influence breast cancer and modulate hormone receptor status. The purpose of this translational study was to investigate how coffee may affect breast cancer growth in relation to estrogen receptor-alpha (ER) status.

机译：目的：流行病学研究表明，饮食因素（例如咖啡）可能会影响乳腺癌并调节激素受体的状态。这项转化研究的目的是研究咖啡如何与雌激素受体-α（ER）状态相关地影响乳腺癌的生长。

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2015年第8期|共11页
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Rosendahl Ann H.; Perks Claire M.; Zeng Li; Markkula Andrea; Simonsson Maria; Rose Carsten; Ingvar Christian; Holly Jeff M. P.; Jernstrom Helena;
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1. Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer [J] . Rosendahl Ann H., Perks Claire M., Zeng Li, Clinical cancer research: an official journal of the American Association for Cancer Research . 2015,第8期

机译：咖啡因和咖啡酸抑制乳腺癌的生长并改变雌激素受体和胰岛素样生长因子I受体的水平
2. Effects of implants of trenbolone acetate, estradiol, or both, on muscle insulin-like growth factor-I, insulin-like growth factor-I receptor, estrogen receptor-α, and androgen receptor messenger ribonucleic acid levels in feedlot steers [J] . Dayton?W. R. Journal of animal science . 2008,第12期

机译：醋酸群勃龙和/或雌二醇植入物对肥育场肉牛肌肉中胰岛素样生长因子-I，胰岛素样生长因子-I受体，雌激素受体-α和雄激素受体信使核糖核酸水平的影响
3. Expression of receptors for epidermal growth factor and insulin-like growth factor I by ZR-75-1 human breast cancer cell variants is inversely related: the effect of steroid hormones on insulin-like growth factor I receptor expression [J] . HW van den Berg, D Claffie, M Boylan, British Journal of Cancer . 1996,第4期

机译：ZR-75-1人乳腺癌细胞变体表达表皮生长因子和胰岛素样生长因子I的受体呈负相关：类固醇激素对胰岛素样生长因子I受体表达的影响
4. Is the Mannose-6-Phosphate/Insulin-Like Growth Factor 2 Receptor Coded by a Breast Cancer Suppressor Gene? [C] . Guy Joseph Lemamy, Majida Esslimani Sahla, Marie Laurence Berthe, International Symposium on Hormonal Carcinogenesis . 2008

机译：是由乳腺癌抑制基因编码的甘露糖-6-磷酸盐/胰岛素样生长因子2？
5. Development of an insturmal method to evaluate insulin receptors and insulin-like growth factor-1 receptors homodimers and hybrid receptors in breast cancer. [D] . Shebani, Karima A. 2016

机译：开发了一种评估乳腺癌中胰岛素受体和胰岛素样生长因子-1受体同型二聚体和杂合受体的可靠方法。
6. Expression of receptors for epidermal growth factor and insulin-like growth factor I by ZR-75-1 human breast cancer cell variants is inversely related: the effect of steroid hormones on insulin-like growth factor I receptor expression. [O] . H. W. van den Berg, D. Claffie, M. Boylan, 1996

机译：ZR-75-1人乳腺癌细胞变异体表达表皮生长因子和胰岛素样生长因子I的受体呈负相关：类固醇激素对胰岛素样生长因子I受体表达的影响。
7. Caffeine and caffeic acid inhibit growth and modify estrogen receptor (ER) and insulin-like growth factor I receptor (IGF-IR) levels in human breast cancer. [O] . Rosendahl, Ann, Perks, Claire M, Zeng, Li, 2015

机译：咖啡因和咖啡酸抑制人乳腺癌中的生长并改变雌激素受体（ER）和胰岛素样生长因子I受体（IGF-IR）水平。
8. Type-I Insulin-Like Growth Factor Receptor (IGF1R)-Estrogen Receptor (ER) Crosstalk Contributes to Antiestrogen Therapy Resistance in Breast Cancer Cells. [R] . Fagan, D. 2013

机译：I型胰岛素样生长因子受体（IGF1R） - 雌激素受体（ER）串扰有助于乳腺癌细胞中的抗雌激素治疗抗性。

Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer

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