Synthesis of functionalised phosphonates or phosphoranes by reaction between trialkyl phosphites or triphenylphosphine, dimethyl acetylenedicarboxylate and aldehyde ethyl carbazones

摘要

Protonation of the reactive intermediate produced from the reaction between trialkyl phosphites and dimethyl acetylenedicarboxylate by ethyl carbazones of aromatic aldehydes following by conjugate addition of the anion of ethyl carbazone on the phosphonium salt intermediate leads to functionalised phosphonates in good yields. Triphenylphosphine also reacted with dimethyl acetylenedicarboxylate and ethyl carbazones to produce functionalised phosphoranes in good yields.