Novel and efficient one-pot synthesis of N-alkyl-N, N-dimethylacetamidines

摘要

An efficient method for the synthesis of N′-alkyl-N,N-dimethylacetamidine derivatives under mild conditions and in excellent yields involved reacting primary alkylamines with N,N-dimethylacetamide in the presence of LiCl as a catalyst and methanol as the acetalising reagent.