Chromone studies. Part 9. Dynamic NMR analysis of rotational isomerism in 2-(N,N-diarkylamino)chromones

摘要

Dynamic H-1 NMR spectroscopy has been used to explore the influence of substituents on the internal rotation of the amino group in a series of twelve 2-(N,N-dialkylamino)chromones; the rotational barriers (Delta G*) in CDCl3 and CD2Cl2 were found to range from 38 to 52 kJ mol(-1).