Samarium triiodide mediated dethiocyanation of phenacyl thiocyanates and its application in carbon-carbon bond formation reactions

摘要

Promoted by Sml(3), phenacyl thiocyanates can undergo efficiently dethiocyanation and thus give a samarium enolate intermediate. On treatment with water or aldehydes and water subsequently, this in situ generated intermediate can give acetophenones or alpha,beta-unsaturated ketones respectively in high yields under mild conditions. [References: 23]