Possible reduced effectiveness of the 2009 H1N1 component of live, attenuated influenza vaccine.

摘要

The Naval Health Research Center (NHRC) in San Diego, California, conducts febrile respiratory illness (FRI) surveillance in civilian and Department of Defense populations at multiple sites across the United States-detecting the first 2 documented cases of a novel, quadruple-reassorted A/H1N1 virus (pHlNl) in California in April 2009 [1]. The NHRC's ongoing febrile respiratory illness surveillance at US military recruit training centers [2] through the initial weeks of the current influenza season suggests poor efficacy for the pHlNl component of the seasonal live, attenuated influenza vaccine (LAIV).