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Use of ICE for RF ablation of AF.

机译:ICE用于房颤的射频消融。

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摘要

Catheter ablation of atrial fibrillation (AF) continues to gain popularity. Despite little to suggest that an improvement in longevity can be achieved through aggressive restoration of sinus rhythm, AF often proves highly symptomatic and its management a challenge. Although atrioventricular (AV) node ablation and pacemaker implantation can regularize heart rate and improve symptoms in many patients with refractory symptomatic AF, there are legitimate concerns over rendering patients' pacemaker dependent unless other options are not available. As a result, the quest for a perfect AF ablation protocol continues. As with many areas in medicine, our understanding grows as we attempt to perfect our techniques and tools.Over time, AF ablation has moved from the creation of linear lesions to the isolation of pulmonary veins (PV) when the former, using older tools, was found lacking in success and high in complications. Approaching focal ablation with tight circumferential lesions was associated with relatively high rates of PV stenosis and hence, lesions were moved further away from the PV os to create large circumferential lesions encompassing pairs of PV. As these lesions moved away from the os, in addition to isolation, substrate modification was performed through the creation of significant atrial conduction/innervation alterations. Hence, we have again moved on from focal isolation to focal plus substrate modification. While most agree that ablation in the normal or near-normal heart is most likely to be successful with the least likelihood of complications, the boundaries continue to be pushed in terms of finding the acceptable AF ablation candidate pool and techniques. Still lacking, of course, is substantiation of the extent over time that patients derive benefit from AF ablation.
机译:房颤(AF)导管消融术继续普及。尽管很少有人暗示可以通过积极恢复窦性心律来延长寿命,但房颤常常被证明具有高度症状,并且其管理是一个挑战。尽管在许多难治性症状性房颤患者中房室结(AV)消融和起搏器植入可以调节心律并改善症状,但除非有其他选择,否则仍存在使患者依赖起搏器的合理担忧。结果,对完美的AF消融方案的追求仍在继续。与医学的许多领域一样,随着我们尝试完善技术和工具,我们的理解也在不断增长。随着时间的流逝,房颤消融已经从线性病变的产生转移到了隔离肺静脉(PV),而前者则使用较旧的工具,被发现缺乏成功和高并发症。局灶性消融伴有紧密的周围病变与相对较高的PV狭窄相关,因此,病变会进一步远离PV os移出,从而形成包含成对PV的较大的周围病变。随着这些病变远离os移开,除了隔离,还通过创建明显的心房传导/神经支配改变来进行基质修饰。因此,我们再次从焦点隔离转向焦点加基板的修改。尽管大多数人认为正常或接近正常的心脏消融最有可能成功,而并发症的可能性最小,但在寻找可接受的AF消融候选对象和技术方面,界限不断地被突破。当然,仍然缺乏对患者从房颤消融中获益的长期证据。

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