The purpose of this study was to test the hypothesis that children with developmental delay without regression of unknown etiology are more likely to have intracranial incidental findings than are children with autistic spectrum disorder or children with normal development. Of 771 patients with magnetic resonance images, 363 (47.1%) patients had developmental delay, 55 (7.1%) had autistic spectrum disorders, and 353 (45.8%) were developmentally normal. Developmentally delayed children were more likely than those with normal development (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.3-2.5; P < .001) or those with autistic spectrum disorder (OR, 2.1; 95% CI, 1.1-4.1; P = .019) to have an intracranial incidental finding. We report a higher prevalence of intracranial incidental findings in children with developmental delay as compared with those children with normal development. Future study should confirm whether the result of this study is merely incidental or truly related to a subgroup of children with developmental disability.
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机译：这项研究的目的是检验以下假设：发育迟缓儿童而没有未知病因的消退比患有自闭症谱系障碍儿童或发育正常的儿童更有可能发生颅内偶然发现。在771例具有磁共振图像的患者中，有363例（47.1％）有发育延迟，55例（7.1％）有自闭症谱系障碍，有353例（45.8％）发育正常。发育迟缓儿童比正常发育儿童（优势比[OR]为1.8; 95％置信区间[CI]为1.3-2.5; P <.001）或自闭症儿童（OR为2.1; 95％ CI，1.1-4.1; P = .019），以发现颅内偶发性疾病。我们报告与发育正常的儿童相比，发育迟缓的儿童颅内偶然发现的患病率更高。未来的研究应确认这项研究的结果仅仅是偶然的还是与发育障碍儿童的一个亚组真正相关。
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