Minocycline Effectively Protects the Rabbit's Spinal Cord From Aortic Occlusion-Related Ischemia

Drenger Benjamin; Fellig Yakov; Ben-David Dror; Mintz Bella; Idrees Suhel; Or Omer; Kaplan Leon; Ginosar Yehuda; Barzilay Yair

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Minocycline Effectively Protects the Rabbit's Spinal Cord From Aortic Occlusion-Related Ischemia

机译：米诺环素有效保护兔脊髓免受主动脉闭塞相关的缺血

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Objectives: To identify the minocycline anti-inflammatory and antiapoptotic mechanisms through which it is believed to exert spinal cord protection during aortic occlusion in the rabbit model.

机译：目的：确定米诺环素的抗炎和抗凋亡机制，据认为可通过这种机制在兔模型的主动脉闭塞过程中发挥脊髓保护作用。

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来源
《Journal of cardiothoracic and vascular anesthesia 》 |2016年第2期| 共9页
作者
Drenger Benjamin; Fellig Yakov; Ben-David Dror; Mintz Bella; Idrees Suhel; Or Omer; Kaplan Leon; Ginosar Yehuda; Barzilay Yair;
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正文语种 eng
中图分类胸部外科学 ;
关键词
induced cord ischemia; hyperglycemia; minocycline; neuroprotection; phosphatidylinositol 3-kinase pathway rabbit model;

机译：诱发的脊髓缺血;高血糖;米诺环素;神经保护;磷脂酰肌醇3-激酶途径的兔模型;

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专利

1. Minocycline Effectively Protects the Rabbit's Spinal Cord From Aortic Occlusion-Related Ischemia [J] . Drenger Benjamin, Fellig Yakov, Ben-David Dror, Journal of cardiothoracic and vascular anesthesia . 2016 ,第2期

机译：米诺环素有效保护兔脊髓免受主动脉闭塞相关的缺血
2. Ischemic Preconditioning Protects against Spinal Cord Ischemia-Reperfusion Injury in Rabbits by Attenuating Blood Spinal Cord Barrier Disruption [J] . Bo Fang, Hong Ma, Huang-Wei Lv, International Journal of Molecular Sciences . 2013 ,第5期

机译：缺血预处理可通过减轻血液中脊髓屏障的破坏来防止家兔脊髓缺血再灌注损伤
3. Evaluation of the neuroprotective effect of minocycline in a rabbit spinal cord ischemia model [J] . WatanabeK., KawaguchiM., KitagawaK., Journal of cardiothoracic and vascular anesthesia . 2012 ,第6期

机译：米诺环素对家兔脊髓缺血模型神经保护作用的评价
4. Nuclear factor-kappa B decoy protects spinal cord injury following ischemia/reperfusion in rats [C] . Masami Nishio, Takamichi Yuguchi, Chihiro Akiyama, International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia . 2003

机译：核因子-Kappa B诱饵保护大鼠缺血/再灌注后的脊髓损伤
5. Minocycline as a neuroprotective agent following spinal cord injury. [D] . Stirling, David Paul. 2005

机译：米诺环素作为脊髓损伤后的神经保护剂。
6. Ischemic Preconditioning Protects against Spinal Cord Ischemia-Reperfusion Injury in Rabbits by Attenuating Blood Spinal Cord Barrier Disruption [O] . Bo Fang, Xiao-Man Li, Xi-Jia Sun, 2013

机译：缺血预处理可通过减轻血液中脊髓屏障的破坏来防止家兔脊髓缺血再灌注损伤
7. Ischemic Preconditioning Protects against Spinal Cord Ischemia-Reperfusion Injury in Rabbits by Attenuating Blood Spinal Cord Barrier Disruption [O] . Bo Fang, Xiao-Man Li, Xi-Jia Sun, 2013

机译：缺血预处理减轻兔脊髓缺血再灌注损伤减轻血栓屏障破坏
8. Evaluation of Hyperbaric Oxygen Therapy in the Treatment of Spinal Cord Injury Using the Rabbit Spinal Stroke Model. [R] . Harrison, C. M., Slayter, M. V., Anderson, L. H., 1990

机译：高压氧治疗兔脊髓损伤模型评价脊髓损伤。

Minocycline Effectively Protects the Rabbit's Spinal Cord From Aortic Occlusion-Related Ischemia

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