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首页> 外文期刊>Journal of cardiothoracic and vascular anesthesia >Thinking beyond the aortic valve: implications of a diseased aorta.
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Thinking beyond the aortic valve: implications of a diseased aorta.

机译:超越主动脉瓣思考:患病的主动脉的影响。

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摘要

THE CASE presented by Bottiger et al is an excellent example of a well-laid management plan that was derailed by an unexpected finding of severe atherosclerotic disease in the aorta, especially in its ascending portion. There were 2 important issues raised by the rinding of a "porcelain" aorta and the surgical limitations it posed. The first decision was whether the aortic valve needed to be replaced under these conditions. Although the American Heart Association guidelines on the management of patients with valvular disease recommend aortic valve replacement for moderate aortic stenosis (AS) if the patient is undergoing coronary artery bypass graft (CABG) surgery (class IIa, level of evidence B), they do not account for the confounding presence of aortic atherosclerotic disease. If the decision is made not to replace the aortic valve, the implications of leaving a moderately ste-nosed aortic valve alone arise. Given the patient's age (77 years) and concurrent coronary disease, the rate of progression of AS would be accelerated, and the patient would be at high risk of developing severe AS within the next 3 years, assuming an average increase of 7 mmHg/year. At this point, the expected mortality risk increases dramatically. However, this longer-term risk must be counterbalanced by the absolute increase in short-term risk incurred by manipulating a porcelain aorta. The additional concern was the minimal decrease in gradient that would be enabled with a prosthetic valve in the aortic position.
机译:Bottiger等人提出的案例是一个精心安排的管理计划的极好例子,该计划因意外发现主动脉中严重的动脉粥样硬化疾病而出轨,尤其是在升主动脉部分。冲洗“瓷器”主动脉及其造成的手术限制引起了两个重要问题。第一个决定是在这些情况下是否需要更换主动脉瓣。尽管美国心脏协会关于瓣膜疾病患者的治疗指南建议,如果患者正在接受冠状动脉搭桥术(CABG)手术(IIa级,证据级别B),则应行主动脉瓣置换术治疗中度主动脉狭窄(AS),但他们确实不能解释主动脉粥样硬化疾病的混杂存在。如果决定不更换主动脉瓣,则会产生仅保留适度的鼻尖主动脉瓣的隐患。考虑到患者的年龄(77岁)和并发的冠状动脉疾病,AS的发展速度将会加快,并且假设在未来3年内,患者平均每年增加7 mmHg的风险,可能会出现严重的AS 。在这一点上,预期的死亡风险急剧增加。但是,必须通过操作瓷主动脉引起的短期风险的绝对增加来抵消这种长期风险。另一个问题是在主动脉位置使用人工瓣膜可使梯度最小化。

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