Determination of glycated haemoglobin (HBG) and its correlation with fasting plasma glucose in the camel.

摘要

Glycated haemoglobin (HbG) concentration is a retrospective measure of mean blood glucose level and is not affected by recent stresses, food ingestion or exercise. HbG has been determined in various wild and domestic animals such as kestrels, markhor, mouflon, aoudad, deer, goat, sheep, dog, camel and horse. But there is no information about HbG in Iranian crossbred camels. On the other hand, relation of HbG to blood glucose and its value in metabolic profiling has not been clarified in the camel. The purpose of this study were to determine normal value of glycated haemoglobin in adult Iranian crossbred camels and to investigate its relation to fasting plasma glucose. Blood samples were collected from jugular veins of 45 clinically healthy adult camels (20 males and 25 females). After separation and washing of red blood cells, hemolysate was prepared and subjected to weak cation exchange chromatography for determination of HbG. Glucose was measured in plasma samples. Plasma glucose and HbG in the camels were 109.7+or-13.24 mg/dl and 4.12+or-0.96% of total haemoglobin. It was shown that HbG% and plasma glucose correlated together (r=0.78, p<0.05).