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Inhaled corticosteroids: the last 5 years

机译:吸入皮质类固醇:最近5年

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摘要

This review will highlight new information on the use of inhaled corticosteroids (ICSs) for management of asthma with regard to long-term side effects and new treatment approaches. Variability in response to ICSs has been increasingly recognized and contribution of pharmacogenomic, phenotypes and environmental factors have been identified and discussed here. As ICSs remain the cornerstone of persistent asthma management, the CAMP trial provides more data in long-term adverse effect of ICSs. In order to minimize the side effects of ICSs, different asthma management approaches have been proposed in different patient populations. In addition, potential advantages of fine particle ICSs for improving small airway disease have been discussed.
机译:这篇综述将着重介绍吸入性类固醇(ICSs)用于哮喘治疗的长期副作用和新的治疗方法方面的新信息。响应ICSs的可变性已得到越来越多的认可,并且在这里已经确定并讨论了药物基因组学,表型和环境因素的贡献。由于ICS仍然是持续治疗哮喘的基石,因此CAMP试验提供了有关ICS长期不良反应的更多数据。为了使ICS的副作用最小化,已经在不同的患者人群中提出了不同的哮喘治疗方法。另外,已经讨论了细粒ICS在改善小气道疾病中的潜在优势。

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