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首页> 外文期刊>Journal of bronchology & interventional pulmonology >Biomechanical Properties of Airway Stents: Implications for Clinical Practice
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Biomechanical Properties of Airway Stents: Implications for Clinical Practice

机译:气道支架的生物力学特性:对临床实践的启示

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摘要

In patients with central airway obstruction (CAO), expected results and adverse events after stent insertion are directly related to the biomechanical properties of the various airway stents (Table 1). A thorough understanding of these biomechanical properties, particularly retrievability, stent size, expansive radial force, fatigability, resistance to buckling, and hydrophilic properties, is critical for appropriate stent selection and for prevention of complications. In this editorial, we will address these properties as pertinent to the practice of bronchoscopists caring for patients requiring airway stents. Operators contemplating stent insertion must consider stent retrievability, as airway stents may be required only for a short duration. This is the case in patients with malignant obstruction who respond to chemotherapy and/or radiation therapy or in patients with benign obstruction, such as postintubation tracheal stenosis, when occasionally stents may be successfully removed without stricture recurrence. More importantly, however, stents need to be removed when stent-related complications occur. In fact, stent fracture, excessive granulation tissue, and epithelialization as can be seen with metallic stents (uncovered, partially or fully covered) may result in embedding of the stent in the airway wall, which potentially precludes a safe stent removal. Published literature suggests that self-expandable metallic stents (SEMS) are "difficult" to remove after 3 months in vivo; however, there are case reports of SEMS removal 10 years after insertion.
机译:对于患有中心气道阻塞(CAO)的患者,支架置入后的预期结果和不良事件与各种气道支架的生物力学特性直接相关(表1)。透彻了解这些生物力学特性,尤其是可收回性,支架尺寸,径向力,疲劳性,抗屈曲性和亲水性,对于选择合适的支架和预防并发症至关重要。在这篇社论中,我们将针对支气管镜医师护理需要气道支架的患者的实践,探讨这些特性。打算插入支架的操作人员必须考虑支架的可收回性,因为可能仅在很短的时间内需要使用气道支架。对于对化学疗法和/或放射疗法有反应的恶性梗阻患者,或在插管后气管狭窄等良性梗阻患者中,有时可以成功取出支架而无狭窄复发的情况。然而,更重要的是,当发生与支架相关的并发症时,需要移除支架。实际上,如金属支架(未覆盖,部分或完全覆盖)所见,支架破裂,过多的肉芽组织和上皮形成可能导致支架嵌入气道壁,这有可能妨碍安全地移除支架。已发表的文献表明,自膨胀金属支架(SEMS)在体内3个月后很难去除。但是,有插入10年后去除SEMS的病例报告。

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