The cell-engineered construct of cartilage on the basis of biopolymer hydrogel matrix and human adipose tissue-derived mesenchymal stromal cells (in vitro study)

摘要

The study results of in vitro formation of tissue-engineered cartilage construct on the basis of cell-engineered construct composed of biopolymer hydrogel matrix and human adipose tissue-derived mesenchymal stromal cells (hADSCs) are presented. It was revealed that hADSCs in biopolymer hydrogel matrix Sphero (R) RGEL under chondrogenic conditions generate three-dimensional structures and pro-duce cartilaginous extracellular matrix components: collagen type II and glycosaminoglycans. (C) 2014 Wiley Periodicals, Inc.