Molecular characterization of novel immunodominant molybdenum cofactor biosynthesis protein Cl (Rv3111) from Mycobacterium tuberculosis H37Rv

摘要

Background: In the molybdenum cofactor biosynthesis pathway, MoaA and MoaC catalyze the first step of transformation of GTP to cPMP. In M. tuberculosis H37Rv, three different genes (Rv3111, Rv0864 and Rv3324c) encode for MoaC homologs. Out of these three only MoaC1 (Rv3111) is secretory in nature.