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The changing epidemiology of asthma in Shanghai, China

机译:中国上海哮喘流行病学的变化

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Objective: To investigate the prevalence of bronchial asthma in Putuo district in Shanghai, China. Methods: Cross-sectional, community-based study was performed with random sampling of a district with a population of one million. The subjects were residents of the district and six or more years of age. Questionnaire and spirometry were completed in all subjects. Asthma was defined as physician-diagnosed asthma. The results were compared with the asthma study of 40 000 population completed by the same team in Pudong area of Shanghai in 1997. Results: We surveyed 27 042 participants. The prevalence of asthma was 1.8% (488/27 042), much higher than the 0.41% (163/40 000) found in the 1997 survey in Pudong area of Shanghai. In subjects with asthma, current smoking, obesity, gender distribution and the combination of allergic diseases between the two studies had no differences. The most prominent causes of asthma exacerbation were cold air, respiratory infection and dust inhalation. Pulmonary function for 428 asthma patients in Putuo survey was analyzed: 228 (53.3%) patients had FEV1% pred lower than 80%. Asthmatics older than 65 years had lower FEV1% pred than other age groups (p50.01). Conclusions: The prevalence of physician-diagnosed asthma in urban of Shanghai has increased in recent years. The most important causes of asthma exacerbations were cold air, respiratory infection and dust exposure. The proportion of individuals with decreased percent predicted forced expiratory volume of first second increased with age. Strengthening the prevention and treatment of asthma, especially in children with asthma, may decrease the health burden of asthma in the urban Chinese population.
机译:目的:调查上海市普陀区支气管哮喘的患病率。方法:以社区为基础的横断面研究是对人口为100万的一个地区进行随机抽样。受试者是该地区的居民,并且年龄在六岁或以上。在所有受试者中完成问卷和肺活量测定。哮喘被定义为医生诊断的哮喘。将该结果与同一小组于1997年在上海浦东完成的4万人口哮喘研究进行了比较。结果:我们调查了27042名参与者。哮喘的患病率为1.8%(488/27 042),远高于1997年上海浦东地区调查的0.41%(163/40 000)。在哮喘患者中,两项研究之间的当前吸烟,肥胖,性别分布和过敏性疾病的合并没有差异。哮喘恶化的最主要原因是冷空气,呼吸道感染和吸入粉尘。普陀调查分析了428名哮喘患者的肺功能:228名(53.3%)患者的FEV1%低于80%。年龄大于65岁的哮喘患者的FEV1%比其他年龄组的患者低(p50.01)。结论:近年来,上海市市区医生诊断的哮喘患病率呈上升趋势。哮喘恶化的最重要原因是冷空气,呼吸道感染和粉尘接触。百分比降低的个体预测的第一秒钟强迫呼气量随年龄增长而增加。加强对哮喘的预防和治疗,尤其是对哮喘患儿,可以减轻中国城市人口哮喘的健康负担。

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