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Altered Apoptosis-Related Signaling After Cardioplegic Arrest in Patients With Uncontrolled Type 2 Diabetes Mellitus

机译:失控的2型糖尿病患者心脏停搏后细胞凋亡相关信号的改变

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摘要

Background-We investigated the effects of cardioplegic arrest and reperfusion (CP/Rep) on myocardial apoptosis and key apoptotic mediators, such as apoptosis-inducing factor, caspase 3, caspase 8, caspase 9, poly(adenosine diphosphate-ribose) polymerase, B-cell lymphoma 2 (Bcl-2) family proteins, and protein kinase C (PKC), in uncontrolled type 2 diabetic, controlled type 2 diabetic, and nondiabetic patients.
机译:背景-我们研究了心脏停搏和再灌注(CP / Rep)对心肌细胞凋亡和关键凋亡介体的影响,例如凋亡诱导因子,胱天蛋白酶3,胱天蛋白酶8,胱天蛋白酶9,聚腺苷二磷酸核糖聚合酶,B -非控制型2型糖尿病,控制型2型糖尿病和非糖尿病患者中的2细胞性淋巴瘤2(Bcl-2)家族蛋白和蛋白激酶C(PKC)。

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