Approche pathogenique de la semiologietomodensitometrique des pneumopathiesinfiltratives diffuses

摘要

The analysis of HRCT findings of interstitial lung diseases frequentlyallows to predict the reversible nature of abnormalities, to recognize theinvolved components of the lung and to suggest the underlying patho-physiological mechanisms. Pathologic alterations in the anatomy of secondary pulmonary lobules include interlobular septal thickening or/and diseases with peripheral lobular distribution, centrilobular abnor-malities, and panlobular abnormalities. Consolidations and groundglass opacities are better analyzed by taking into account the way lungresponds to injury rather than anatomic distribution of lesions. Therecognition of the topographic distribution of lesions and associatedabnormalities, including airway diseases, pulmonary hypertension andembolus, diaphragmatic and pharyngeal dysfunctions, provides a betterunderstanding of underlying disease mechanisms and allows a limiteddifferential diagnosis.