DIRECT AND SIMPLE CONVERSION OF CODEINE TO THEBAINONE-A AND DIHYDROTHEBAINONE

摘要

Abstract-Codeine can be rearranged directly to thebainone-A in 74% yield by treatment with BuLi.Hydrogenation of the curde material followed by crystallization as the hydrochloride salt leads to dihydrothebainone in 78% yield.