Impact of Paclitaxel Dose on Tissue Pharmacokinetics and Vascular Healing A Comparative Drug-Coated Balloon Study in the Familial Hypercholesterolemic Swine Model of Superficial Femoral In-Stent Restenosis

摘要

OBJECTIVES This study sought to compare the effect of paclitaxel-coated balloon (PCB) concentration on tissue levels and vascular healing using 3 different PCB technologies (In. Pact Pacific = 3 mu g/mm(2), Lutonix = 2 mu g/mm(2) and Ranger = 2 mu g/mm(2)) in the experimental setting.