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What caused these itchy white bumps on the wrists?

机译:是什么引起了手腕上这些发痒的白色肿块?

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A 43-year-old man was referred to dermatology for evaluation of lesions on his volar wrists that had been diagnosed as lichen planus. The lesions had been present for several months and were unresponsive to fluocinolone cream and oral cephalexin 500 mg 3 times a day for a week. At times, the lesions itched terribly. The patient was otherwise healthy and had no odier rashes. He had not traveled internationally, been exposed to new animals, or started any medications. No one around him was similarly afflicted. Examination revealed numerous discrete, whitish planar papules and nodules on the patient's volar wrists (Figure 1). The lesions were somewhat atrophic and smooth to the touch. No erythema could be detected, and no other lesions were seen. Punch biopsy showed a lichenoid infiltrate at the dermoepidermal junction and compact hyperkeratosis in die stratum corneum, which was diicker dian the greatly effaced epidermis. Marked edema was also evident in die upper dermis.
机译:一名43岁的男子被转诊至皮肤科,以评估其被诊断为扁平苔藓的手腕腕部病变。病变已存在几个月,对氟辛诺酮乳膏和口服头孢氨苄500 mg每天无反应,一周3次。有时,病变非常剧烈。该患者身体健康,没有皮疹。他没有出国旅行,没有接触过新动物,也没有开过任何药物。他周围没有人受到类似的折磨。检查发现患者手腕上有许多离散的发白的平面丘疹和结节(图1)。病变有些萎缩,摸起来光滑。没有发现红斑,也没有发现其他病变。穿刺活检显示皮肤表皮交界处有苔藓样浸润,角质层紧凑型角化过度,这是表皮脱落的重要部位。上层真皮也有明显的水肿。

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