One-pot synthesis of coumarin derivatives

摘要

An efficient one-pot three-component cyclocondensation reaction for the synthesis of coumarin derivatives 3-(5'-substituted-2'-benzoxa-zolyl)-7-diethylaminocoumarins from 4-diethylaminosalicylaldehyde,ethyl cyanoacetate and 4-substituted-2-aminophenol is described.The novel procedure features short reaction time,moderate yields and simple workup.