Bio- and chemo-informatics beyond data management: crucial challenges and future opportunities.

摘要

Bio- and chemo-informatics are now thought to be crucial to the success and integration of biotechnology and drug discovery. Research in this area has expanded to go beyond data- and information-management. Here, we review exemplary areas, such as target identification and validation, virtual screening, and prediction of downstream characteristics of leads, where further research will play a key role in progressing the field.