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>A rare presentation of an uncommon malignancy: thromboembolism in a patient with a gastrointestinal stromal tumor.
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A rare presentation of an uncommon malignancy: thromboembolism in a patient with a gastrointestinal stromal tumor.
Gastrointestinal stromal tumors (GISTs) are uncommon, with an annual incidence of 10-20 per 10 6persons [1]. GISTs usually arise from mutations in the c-KIT receptor [2]. Approximately 50-60% occur in the stomach and often present as an abdominal mass, pain, or gastrointestinal (GI) bleeding [1]. We describe a patient who presented with deep vein thrombosis (DVT) and pulmonary embolism (PE) and was found to have a GIST.A 48-year-old man presented to the emergency department with left leg pain and dyspnea on exertion that began 1 week earlier. He denied weight loss, abdominal pain, fever, or chills but reported occasional dark bowel movements. He had no history of blood clots, recent travel, or prolonged immobility.
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