Can nutritional biomarkers help to provide the 'missing link' in diet-diabetes associations?

摘要

There are two well-known facts regarding diabetes prevention. First, the prevention of diabetes is important, nay urgent, given its increasing burden, with an estimated 366 million individuals worldwide with diabetes in 2011, projected to rise to 552 million by 2030 [l], and it is a leading cause of death [2]. Second, there is evidence from randomized trials that the primary prevention, or at least the delay of onset, of Type 2 diabetes is possible with lifestyle interventions, including diet [3].