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首页> 外文期刊>Dermatologic surgery >Characteristics of basal cell carcinoma of the lip treated using mohs micrographic surgery
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Characteristics of basal cell carcinoma of the lip treated using mohs micrographic surgery

机译:莫氏显微外科手术治疗唇基底细胞癌的特征

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摘要

Background There is a lack of U.S-based studies on basal cell carcinoma (BCC) of the upper lip treated using Mohs micrographic surgery (MMS). Objective To explore characteristics of BCC of the upper lip treated using MMS. Methods We performed a chart review of BCC cases from 2005 to 2011. Results Two hundred eighty-one cases were identified. There was a slight female predominance (55%). Men had a larger initial (p <.01) and final (p =.03) defect size. Infiltrative tumors had larger initial (p <.01) and final areas (p <.01). Ten percent of tumors were designated recurrent after previous treatment. Recurrent lesions (p <.001) and older age (p =.03) were associated with larger initial size. Complex reconstruction was required: 44% by local flap or graft and 13% by plastic surgery. Conclusion There was a 1.2:1 female to male ratio, in contrast to the previously reported female predominance of 3.5:1. This cohort showed a higher recurrence rate than reported in the literature. Men and elderly patients were also found to have significantly larger initial lesion size. Thirteen percent of patients required repair by plastic surgery, reflecting heightened levels of cosmetic concern. These findings suggest that MMS is important in delineating subclinical tumor spread and providing complex repairs.
机译:背景缺乏基于美国的有关使用Mohs显微外科手术(MMS)治疗的上唇基底细胞癌(BCC)的研究。目的探讨MMS治疗上唇BCC的特征。方法我们对2005年至2011年的BCC病例进行了图表审查。结果确定了281例。女性占少数(55%)。男人的初始缺损(p <.01)和最终缺损(p = .03)较大。浸润性肿瘤的初始区域(p <.01)和最终区域(p <.01)较大。先前治疗后,有10%的肿瘤被指定为复发。复发性病变(p <.001)和年龄较大(p = .03)与较大的初始大小有关。需要进行复杂的重建:局部皮瓣或移植物占44%,整形手术占13%。结论男女比例为1.2:1,而先前报道的女性比例为3.5:1。该队列的复发率高于文献报道。男性和老年患者也发现病灶明显更大。 13%的患者需要通过整形手术进行修复,这反映出对美容的关注程度提高了。这些发现表明,MMS在描述亚临床肿瘤扩散和提供复杂修复方面很重要。

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