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Scleroderma and Raynaud's phenomenon improve with high-peak power laser therapy: A case report

机译:高峰值功率激光治疗可改善硬皮病和雷诺现象:一例病例报告

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摘要

Photobiotherapy is the clinical application of light for healing decubitus ulcers and other superficial wounds. Mester and colleagues, who reported healing of chronic soft tissue ulcers with application of a low-energy (1-4 J/cm~2) ruby laser introduced low-level laser therapy (LLLT) as a therapeutic modality.2 They studied more than 1,000 human cases of recalcitrant ulcers of different etiology and reported improvement in more than 70% of those cases using various laser systems with a dose of approximately 4J/cm~2. Subsequent studies have followed, studying LLLT in Raynaud's phenomenon and diabetic microangiopathy. A case report by Eisen and Alster demonstrated marked softening of a sclerotic morphea plaque and improvement in skin coloration with the use of a 585-nm pulsed dye laser without side effects or complications.3 In a study of LLLT using an 890-nm diode laser by Ezzati and colleagues, irradiation of third-degree burns on rats demonstrated greater wound closure rate.4 This case report supports the use of a novel laser not previously reported in the treatment of systemic sclerosis and Raynaud's phenomenon.
机译:光生物疗法是光疗法在治疗褥疮和其他浅表伤口方面的临床应用。梅斯特(Mester)和同事报告了通过使用低能量(1-4 J / cm〜2)红宝石激光治疗慢性软组织溃疡的方法,并引入了低水平激光疗法(LLLT)作为治疗手段。2 1,000例不同病因的顽固性溃疡人类病例,据报道,使用剂量约为4J / cm〜2的各种激光系统,其中70%以上的病例得到了改善。随后进行了后续研究,研究了雷诺氏现象和糖尿病性微血管病的LLLT。艾森(Eisen)和阿尔斯特(Alster)的一例病例报告显示,使用585 nm脉冲染料激光可显着软化硬化的吗啡斑块并改善皮肤着色。3在使用890 nm二极管激光的LLLT研究中由Ezzati等人进行的研究表明,对大鼠进行三度烧伤的照射显示出更高的伤口闭合率。4该病例报告支持使用以前未曾报道过的新型激光治疗全身性硬化症和雷诺现象。

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