The structure of the product formed by condensation of malononitrile with dialkyl acetone-1,3-dicarboxylates

摘要

By the condensation of malononitrile (1) with dialkyl acetone-1,3- dicarboxylates 2a, b alkyl (3-cyano-6-alkoxy-2-oxo-1,2-dihydropyridin-4-yl) acetates 6a, b are formed in contrast to an earlier report according to which diethyl 3-(dicyanomethylene)glutarate 3b was obtained in the reaction of 1 and 2a. Compounds 6a, b were transformed with DMFDMA into the corresponding (E)-alkyl 2-(3-cyano-6-alkoxy-2-oxo-1,2-dihydropyridin-4-yl)-3-(dimethylamino) propenoates 7a, b. The structures of 6a and 7a were confirmed by X-ray structural analysis.