Implementation of an Antimicrobial Stewardship Program in a Community Hospital: Results of a Three-Year Analysis

摘要

Background: In July 2007, the Pharmacy Department at Suburban Hospital implemented an antimicrobial stewardship program (ASP) using existing clinical pharmacy resources that did not include an on-site infectious diseases (ID) pharmacist. Medical staff personnel were supportive of the ASP, but there were no ID physician resources actively dedicated to the program. Remote access to an ID pharmacist was available.Objectives: This program evaluated the impact of a pharmacy-driven ASP on cost, antimicrobial utilization, and quality indicators in a community hospital with limited ID professional resources. Methods: The tenets of the program were adopted from recommendations in the most current Infectious Diseases Society of America/Society for Healthcare Epidemiology of America antimicrobial stewardship guidelines. Antimicrobial utilization, cost, prospective medication use data, and interventions were tracked using customized spreadsheets. Three years of utilization and cost data were captured to provide a baseline and post implementation comparison. Results: Antimicrobial utilization decreased 5.2% compared to baseline (P < .001) as measured by the defined daily dose (DDD) per 1,000 patient days. The associated cost reduction during the period was 24% compared to baseline (P < .001), resulting in estimated savings of approximately $290,000. Quality of care indicators improved, and physicians were responsive to daily clinical pharmacist review and pharmacy interventions.Conclusions: An ASP can be implemented in a community hospital setting with existing clinical pharmacy resources that do not include an ID specialist dedicated full time to the program. Prospective monitoring of antimicrobial usage resulted in decreased antimicrobial cost and utilization and improvements on key quality of care indicators. Based on this evidence of success, the program continues.