Multicomponent Approach Towards the Synthesis of Substituted Pyrroles under Supramolecular Catalysis Using,beta-Cyclodextrin as a Catalyst in Water Under Neutral Conditions

摘要

Synthesis of substituted pyrroles in H2O by using beta-cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good-to-excellent yields (79-89%). The supramolecular catalysis of the reaction was studied using H-1-NMR spectroscopy. beta-Cyclodextrin can be recovered and reused several times without loss of activity.