Describing the role of ethnicity in the progression of NAFLD: Easier said than done?

摘要

We thank Dr. Holt for his interest in our study investigating associations between ethnicity and nonalcoholic fatty liver disease (NAFLD) using data from the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), and we appreciate the positive comments regarding our study made by Dr. Holt in his letter.Dr. Holt reiterates the importance of 2 key variables related to the analysis of NAFLD histologic severity, namely age and the role of the PNPLA3 rs738409 polymorphism that we had described in detail in the Discussion section of our article.