Venous blood ammonia can be associated with cerebral blood flow in hepatic encephalopathy

摘要

To the Editor:We read the study by Dam et al. with great interest. They compared the cerebral oxygen metabolism (CMRO2), cerebral blood flow (CBF), and metabolic rate of blood ammonia (CMRA) in patients with cirrhosis during and after recovery from hepatic encephalopathy (HE) and concluded that the changes in CMRO2 and CBF could not link to ammonia concentration or CMRA. Their findings are of great potential for clinical applications; however, we have some concerns.