Systematic Review and Meta-analysis from Chinese Literature: the Association Between Helicobacter pylori Eradication and Improvement of Functional Dyspepsia

摘要

Objectives: To evaluate the effect of eradicating Helicobacter pylori on dyspeptic symptoms in patients with functional dyspepsia in China.Data sources: Randomized controlled trials conducted in China and those published between 1989 and April 2007.Review methods: The articles were retrieved from Chinese biomedicine Web database and Chinese scientific Journals database using proper MESH headings and assessed by two independent investigators according to established inclusion criteria. The characteristics of chosen articles were displayed for further analysis, and summary odds ratio were calculated to determine the overall effect of H. pylori eradication. All the data were entered and analyzed using review manager 4.1, and p < .05 was defined as statistically significant in all analysis.