Various predisposing factors are required to cause clinical and subclinical Necrotic Enteritis. Controlling these factors will, up to a large extend, reduce economic losses. It is generally accepted that predisposing factors are required for Clostridium perfringens to cause Necrotic Enteritis (NE). The best known predisposing factor is mucosal damage caused by coccidiosis, in particular by Eimeria species that colonise the small intestine (E. maxima, E. mitis, E. acervulina).
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