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Metallic ureteral stents in malignant ureteral obstruction: Short-term results and radiological features predicting stent failure in patients with non-urological malignancies

机译:金属输尿管支架置入恶性输尿管梗阻:短期结果和影像学特征可预测非泌尿系统恶性肿瘤患者的支架衰竭

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Purpose: To provide short-term result of the metallic ureteral stent in patients with malignant ureteral obstruction and identify radiological findings predicting stent failure. Materials and methods: The records of all patients with non-urological malignant diseases who have received metallic ureteral stents from July 2009 to March 2012 for ureteral obstruction were reviewed. Stent failure was detected by clinical symptoms and imaging studies. Survival analysis was used to estimate patency rates and factors predicting stent failure. Results: A total of 74 patients with 130 attempts of stent insertion were included. A total of 113 (86.9 %) stents were inserted successfully and 103 (91.2 %) achieved primary patency. After excluding cases without sufficient imaging data, 94 stents were included in the survival analysis. The median functional duration of the 94 stents was 6.2 months (range 3-476 days). Obstruction in abdominal ureter (p = 0.0279) and lymphatic metastasis around ureter (p = 0.0398) were risk factors for stent failure. The median functional durations of the stents for abdominal and pelvic obstructions were 4.5 months (range 3-263 days) and 6.5 months (range 4-476 days), respectively. The median durations of the stents with and without lymphatic metastasis were 5.3 months (range 4-398 days) and 7.8 months (range 31-476 days), respectively. Conclusion: Metallic ureteral stents are effective and safe in relieving ureteral obstructions resulting from non-urological malignancies, and abdominal ureteral obstruction and lymphatic metastasis around ureter were associated with shorter functional duration.
机译:目的:提供金属输尿管支架治疗恶性输尿管梗阻患者的近期结果,并确定可预测支架衰竭的影像学表现。材料和方法:回顾了所有自2009年7月至2012年3月因输尿管阻塞而接受金属输尿管支架治疗的非泌尿系统恶性疾病患者的记录。通过临床症状和影像学检查发现支架衰竭。生存分析用于估计通畅率和预测支架衰竭的因素。结果:总共74例患者进行了130次支架插入尝试。总共成功插入了113个(86.9%)支架,其中103个(91.2%)达到了第一通畅。在排除没有足够影像数据的病例后,将94个支架纳入生存分析。 94个支架的中位功能持续时间为6.2个月(范围3-476天)。腹部输尿管阻塞(p = 0.0279)和输尿管周围淋巴结转移(p = 0.0398)是支架失效的危险因素。腹部和骨盆梗阻支架的中位功能持续时间分别为4.5个月(3-263天)和6.5个月(4-476天)。有和没有淋巴转移的支架的中位持续时间分别为5.3个月(4-398天)和7.8个月(31-476天)。结论:金属输尿管支架可有效,安全地缓解非泌尿系恶性肿瘤引起的输尿管梗阻,而输尿管周围的腹部输尿管梗阻和淋巴结转移与功能持续时间较短有关。

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