Bleaching systems and thickening agents lead to changes in the tooth enamel matrix as a result of an unspecific oxidation of the bleaching gel in the enamel. This reaction may result in a loss of mineral content and a decrease in microhardness. The aim of this study was to evaluate the effects of different bleaching systems and their thickening agents on the microhardness of human enamel in situ. Two dental slabs (3 x 3 x 2 mm) obtained from third molars were fixed on the buccal facial aspects of the maxillary first molars in a group of 45 volunteers. The volunteers were treated with 10% carbamide peroxide gel with carbopol as the thickening agent (group 1), 2% carbopol gel (group 2), 10% carbamide peroxide paste with poloxamer as the thickening agent (group 3), poloxamer (group 4), or 6.5% hydrogen peroxide strips for 21 days (group 5) (experimental treatment factor). The effects of the experimental treatment were evaluated by microhardness tests performed both before and after treatment (time factor). Data were submitted to split-plot analysis of variance and Tukey tests. Only time showed a statistically significant difference (P < .0001). All treatments reduced the enamel microhardness during treatment. Clinically, a reduction in microhardness can be expected after dental bleaching.
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机译：漂白系统和增稠剂会导致牙釉质基质发生变化，这是由于牙釉质中的漂白凝胶发生非特异性氧化所致。该反应可能导致矿物质含量减少和显微硬度降低。这项研究的目的是评估不同的漂白体系及其增稠剂对人类牙釉质显微硬度的影响。在一组45名志愿者中，将由第三磨牙获得的两块牙板（3 x 3 x 2 mm）固定在上颌第一磨牙的颊面部。志愿者接受10％过氧化脲凝胶，以卡波姆作为增稠剂（第1组），2％过氧化脲凝胶（第2组），以泊洛沙姆为增稠剂的10％过氧化脲糊剂（第3组），泊洛沙姆（第4组）进行治疗。 ）或6.5％的过氧化氢试纸连续21天（第5组）（实验治疗因子）。通过在治疗之前和之后进行的显微硬度测试（时间因子）评估了实验处理的效果。将数据提交给方差和Tukey检验的分割图分析。只有时间显示出统计学上的显着差异（P <.0001）。所有处理均降低了处理过程中牙釉质的显微硬度。临床上，可以预期牙齿漂白后显微硬度会降低。
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