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Antimicrobial stewardship programs (ASPs): The devil is in the details

机译:抗菌素管理计划(ASP):细节在于魔鬼

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Infectious disease clinicians traditionally have had the leadership role in recommending appropriate and optimal use of antibiotics in hospitals. This judicious and optimized use of antimicrobial agents is the central principle of antimicrobial stewardship. In addition to increased awareness among infectious disease experts, antimicrobial stewardship has become a national priority. Recently, the US Food and Drug Administration (FDA) promoted antimicrobial stewardship by creating incentives to encourage new anti-infective research. The Infectious Diseases of Society of America (IDSA) launched the campaign "Bad Bugs, No Drugs" to plead for the development of new systemic antibiotics.1 While efforts at stewardship are important in their own right, the relative paucity of new agents and the spread of multidrug-resistant organisms have further emphasized the need for antimicrobial stewardship programs (ASPs) in order to preserve the antimicrobial agents that are currently available.
机译:传统上,传染病临床医生在推荐适当和最佳使用抗生素的医院中起着领导作用。明智和优化地使用抗菌剂是抗菌管理的中心原则。除了提高传染病专家的认识外,抗菌素管理已成为国家的重点。最近,美国食品药品监督管理局(FDA)通过制定激励措施鼓励新的抗感染研究,从而促进了抗菌素管理。美国社会传染病协会(IDSA)发起了“无药可救的臭虫”运动,呼吁开发新的全身性抗生素。1尽管管理工作本身很重要,但相对而言,新药和药物的相对匮乏耐多药生物的传播进一步强调了对抗菌素管理计划(ASPs)的需求,以保存当前可用的抗菌剂。

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