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首页> 外文期刊>Value in health: the journal of the International Society for Pharmacoeconomics and Outcomes Research >Health-related quality of life after total knee replacement or unicompartmental knee arthroplasty in an urban asian population
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Health-related quality of life after total knee replacement or unicompartmental knee arthroplasty in an urban asian population

机译:亚洲城市人口全膝关节置换或单室膝关节置换术后与健康相关的生活质量

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摘要

Objective: To examine health-related quality of life (HRQoL) after total knee replacement (TKR) or unicompartmental knee arthroplasty (UKA). Methods: Asian adult patients undergoing either TKR or UKA in a hospital in Singapore between 2001 and 2006 were interviewed before surgery and 6 and 24 months postoperatively to obtain demographic information and HRQoL scores using the Short Form-36 Health Survey (SF-36) and the Oxford Knee Score (OKS). Results: Data were collected from 2243, 1715, and 1113 patients at baseline and at 6 and 24 months, respectively. TKR patients had a lower preoperative OKS than UKA patients and lower preoperative scores on four subscales of the SF-36 (P < 0.01). Both TKR and UKA patients' OKS and SF-36 subscale scores improved 6 months postoperatively except in the general health domain. SF-36 role physical and bodily pain scores showed the most improvement (40.9 and 33.0 points in TKR and 36.9 and 31.4 points in UKA patients, respectively). Two years after surgery, TKR patients' SF-36 scores and OKSs were not significantly different from those of UKA patients except for physical functioning scores. Multiple regression analysis adjusting for demographics showed that baseline scores were a significant predictor of the postoperative OKSs and scores on all SF-36 subscales (P < 0.01), whereas the type of surgery was not associated with the postoperative scores. Conclusions: Both TKR and UKA patients experienced significant improvements in HRQoL, particularly in the role physical and pain domains. After controlling for potential confound-ing variables, the type of surgery was not a significant predictor of patients' postoperative HRQoL scores.
机译:目的:检查全膝关节置换(TKR)或单室膝关节置换术(UKA)后与健康相关的生活质量(HRQoL)。方法:2001年至2006年在新加坡一家医院接受TKR或UKA治疗的亚洲成年患者,在手术前以及术后6和24个月接受访谈,以使用Short-36-Health Health Survey(SF-36)和SF-36健康调查获得人口统计学信息和HRQoL评分。牛津膝盖得分(OKS)。结果:分别从基线,第6和24个月的2243、1715和1113例患者收集数据。 TKR患者的术前OKS较UKA患者低,术前评分在SF-36的四个子量表上均较低(P <0.01)。 TKR和UKA患者的OKS和SF-36量表评分均在术后6个月有所改善,但在一般健康领域除外。 SF-36角色的身体和身体疼痛评分显示出最大的改善(TKR分别为40.9和33.0分,UKA患者分别为36.9和31.4分)。手术后两年,TKR患者的SF-36评分和OKS与UKA患者的身体功能评分无显着差异。校正人口统计学的多元回归分析表明,基线评分是术后OKS和所有SF-36子量表评分的重要预测指标(P <0.01),而手术类型与术后评分无关。结论:TKR和UKA患者在HRQoL方面都有显着改善,尤其是在身体和疼痛方面。在控制了潜在的混淆变量之后,手术类型不是患者术后HRQoL得分的重要预测指标。

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