Polymorphism rs144848 in BRCA2 may reduce lung cancer risk in women: a case-control study in southeast China

摘要

Purpose: Whereas lung cancer incidence among men has declined in recent years, the incidence rate among women has increased rapidly. Sex could affect DNA repair capacity. Although BRCA2 is important in DNA repair, few data are available on the association between BRCA2 polymorphisms and lung cancer in women. Therefore, we investigated this in a case-control study among Chinese women.