Generation of knockdown mice by CRISPR/Cas9-based targeted insertion of artificial miRNA sequence

Miura Hiromi; Gurumurthy Channabasavaiah B.; Quadros Rolen; Sato Masahiro; Ohtsuka Masato

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Generation of knockdown mice by CRISPR/Cas9-based targeted insertion of artificial miRNA sequence

机译：通过基于CRISPR / Cas9的定向插入人工miRNA序列产生基因敲除小鼠

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来源
《Transgenic research》 |2016年第2期|共1页
作者
Miura Hiromi; Gurumurthy Channabasavaiah B.; Quadros Rolen; Sato Masahiro; Ohtsuka Masato;
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原文格式 PDF
正文语种 eng
中图分类医学遗传学;
关键词
CRISPR/Cas9; RNAi; knockdown; mice;

机译：CRISPR / Cas9;RNAi;敲低;小鼠;

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专利

1. Generation of knockdown mice by CRISPR/Cas9-based targeted insertion of artificial miRNA sequence [J] . Miura Hiromi, Gurumurthy Channabasavaiah B., Quadros Rolen, Transgenic research . 2016,第2期

机译：通过基于CRISPR / Cas9的定向插入人工miRNA序列产生基因敲除小鼠
2. CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA [J] . Hiromi Miura, Channabasavaiah B Gurumurthy, Takehito Sato, Scientific reports. . 2015,第1期

机译：通过使用更长的单链DNA内源插入人工microRNA来产生基于CRISPR / Cas9的基因敲除小鼠
3. CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA [J] . Hiromi Miura, Channabasavaiah B Gurumurthy, Takehito Sato, Scientific reports. . 2015,第1期

机译：通过使用更长的单链DNA内源插入人工microRNA来产生基于CRISPR / Cas9的基因敲除小鼠
4. Computational identification of condition-specific miRNA targets based on gene expression profiles and sequence information [C] . Je-Gun Joung, Zhangjun Fei The 7th Asia-Pacific Bioinformatics Conference（第七届亚太生物信息学大会） . 2009

机译：基于基因表达谱和序列信息的条件特异性miRNA靶标的计算鉴定
5. Modulation of Microrna Expressions in Tomato by Short Tandem Target Mimic and Artificial MiRNAs [D] . Liu, Haiping. 2017

机译：短串联靶模模仿番茄中微小RNA表达的调节
6. CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA [O] . Hiromi Miura, Channabasavaiah B Gurumurthy, Takehito Sato, -1

机译：通过使用更长的单链DNA内源插入人工microRNA来产生基于CRISPR / Cas9的基因敲除小鼠
7. CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences [O] . Y. Lin, T. J. Cradick, M. T. Brown, 2014

机译：CRISPR / CAS9系统在靶DNA与指导RNA序列之间的插入或缺失具有脱靶活动

Generation of knockdown mice by CRISPR/Cas9-based targeted insertion of artificial miRNA sequence

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