Depression, anxiety, and somatoform disorders are among the most prevalent psychiatric disorders; they have overlapping symptoms, and they frequently co-occur. In many respects, however, somatoform disorders, such as somatization disorder, have received the least attention from researchers. First, relatively few randomized controlled trials have been undertaken on these disorders, although some presumably related conditions, such as fibromyalgia, now have Food and Drug Administration approved drug treatments. Second, there are comparatively few studies of the neurobiology of these conditions, although there have been significant advances in the clinical neuroscience of pain. Third, there are few animal models of somatoforrh disorders, although, again, there have been important advances in the basic neuroscience of pain.
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