Evidence of poisoning of piglets due to improper use of insecticides [German]

摘要

A case of organophosphate (OP) poisoning in piglets was investigated to examine the risk of OP poisoning from the application of insecticides. Three known compounds were mixed with one unknown compound by the farmer. This cocktail contained fenvalerate, piperonylbutoxide, the synergist to pyrethroids, dichlorvos and another OP substance. The pesticides were consumed orally by piglets. After a few hours, some pigs were suffering from haemorrhagic diarrhoca, ataxia, partial paralysis, rhinorrhea and bradycardia. A number of piglets died within two days. One of two pigs were successfully treated with atropine. The autopsies revealed haemorrhagic enteritis and fatty change in the liver and renal tubuli cells. The OPs dichlorvos and parathion were detected, by an improved extraction method combined with enzymatic and thin layer chromatography, in the stomach contents and in liver and kidney tissue. The procedure used is suitable for screening and semiquantitative determination of OPs and carbamates in animal and human tissues. In this case, the arbitrarily mixed pesticides resulted in increased neurotoxicity caused by the addition of parathion. The study indicated the risks of insecticide contamination for piglets and the synergistic effects of pyrethroids and OPs.