首页> 外文期刊>The Philippine Agricultural Scientist >Anti-Mycobacterium phlei activity of the bark of Ziziphus talanai (Blanco) Merrill.
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Anti-Mycobacterium phlei activity of the bark of Ziziphus talanai (Blanco) Merrill.

机译:马齿rill(Ziziphus talanai)(Blanco)Merrill的树皮的抗分枝杆菌phlei 活性。

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The bark of Ziziphus talanai (Blanco) Merrill, a tree endemic to the Philippines, is traditionally used in Antique to cure kidney problems such as urinary tract infections (UTI), and skin diseases such as scabies and ringworm. Its antimicrobial activity was screened against several microorganisms to have a more comprehensive anti-infective profile of the plant. The MeOH extract of Z. talanai bark exhibited antimicrobial activity against Gram-positive Mycobacterium phlei, S. aureus and B. subtilis at 20,000 micro g and 2,000 micro g but was inactive against Gram-negative E. coli, P. aeruginosa, C. albicans and S. cerevisiae. It has minimal antifungal activity against T. mentagrophytes. The MeOH extract of Z. talanai is therefore inactive against uncomplicated UTI, which is mostly caused by E. coli. Further bioassay-guided isolation and subsequent spectral analysis yielded ceanothic acid, whose activity is specific to M. phlei at 100 micro g. M. phlei causes chronic ambulatory peritoneal dialysis-associated peritonitis.
机译:菲律宾特有的树 Ziziphus talanai (Blanco)Merrill的树皮在古董中通常用于治疗肾病,例如尿路感染(UTI)以及skin疮和癣等皮肤病。筛选了针对几种微生物的抗微生物活性,以具有更全面的植物抗感染特性。 Z的MeOH萃取物。 talanai树皮对革兰氏阳性分枝杆菌,i表现出抗菌活性。金黄色和 B。枯草杆菌分别为20,000 microg和2,000 micro g,但对革兰氏阴性 E没有活性。大肠杆菌, P。铜绿, C。白化和 S。啤酒。它对 T具有最小的抗真菌活性。薄荷植物。 Z的MeOH萃取物。因此,talanai 对未复杂的UTI无效,后者通常是由 E引起的。大肠杆菌。进一步的生物测定指导的分离和随后的光谱分析产生了ceanothic acid,其活性对iM是特异性的。 phlei 为100微克。 M。静脉炎可引起慢性非卧床腹膜透析相关性腹膜炎。

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