Bovine papillomavirus type 10 with a deletion associated with a lingual papilloma in a cow

摘要

Different types of papillomavirus usually cause papillomas in specific tissues. Previously, bovine papillomavirus (BPV) type 10 has been associated specifically with cutaneous papillomas in cattle. In this study, BPV-10 was detected in a papilloma on the tongue of a cow. Whole genome analysis demonstrated that the sequence of this BPV-10 strain had a 129 base pair deletion in the El open reading frame, which was confirmed by Southern blot analysis, PCR and reverse transcriptase-PCR.