Post-weaning Multisystemic Wasting Syndrome (PMWS) in France: serological profiles of affected versus non-affected herds and preliminary analytic epidemiology

摘要

The serological characteristics of Post-weaning Multisystemic Wasting Syndrome (PMWS) affected and non-affected farms were studied through a case/control survey. This study involved 138 farrow-to-finish farms located in France and selected accordingto their PMWS status defined according to mortality rate, clinical observations and laboratory findings. Blood samples were taken from different categories of pigs including sows and growing pigs and several serological analyses were carried out for Porcine Circovirus type 2 (PCV-2), PRRS virus, parvovirus, influenza viruses and Lawsonia intracellularis antibody detection. The serological profile of the farm was related to the PMWS status with a multivariate logistic regression model. It came out thatPMWS farms were characterised by a higher seroprevalence for PCV-2 in growing pigs at the beginning of the fattening period and a lower seroprevalence in young sows. A strong association was found between PRRS virus and parvovirus active circulation in the herd. A quantitative variation in expression of the disease was observed, suggesting the need for the next analysis of the circumstances related to the syndrome.